Digoxin

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PackageDosagePricePrice per Dose
Dosage: 0,25mg
182317360 pill0,25mg£204.32£0.57
182318180 pill0,25mg£114.55£0.64
182319120 pill0,25mg£86.21£0.72
18232090 pill0,25mg£69.67£0.78
18232160 pill0,25mg£51.96£0.87
18232230 pill0,25mg£31.88£1.05
Digoxin
Digoxin Description

Overview of Digoxin

Digoxin is a medication primarily used to treat certain heart conditions, including atrial fibrillation and heart failure. Its primary function is to help strengthen the heartbeat and promote more efficient blood circulation. As a cardiac glycoside, digoxin has been in use for many decades and remains an important part of cardiovascular therapy. Patients taking this medication need to be closely monitored due to its narrow therapeutic index, which means that the difference between an effective dose and a toxic dose is very small.

How Digoxin Works

Digoxin works by altering the electrical activity of the heart. It inhibits an enzyme called Na+/K+ ATPase in cardiac cells. This results in increased intracellular calcium, which enhances cardiac contractility, making the heart beat stronger. Additionally, digoxin exhibits a slowing effect on the conduction of electrical impulses through the atrioventricular (AV) node. This helps control the rapid and irregular heartbeat associated with atrial fibrillation. Its dual action helps improve symptoms and quality of life for patients with heart failure, although it does not directly improve survival rates in all cases.

Administration and Dosage

Dosage of digoxin must be carefully tailored to each individual. It is often prescribed in low doses to minimize the risk of toxicity. The medication is typically taken orally, once daily, with adjustments based on age, kidney function, and response to therapy. Regular blood tests are necessary to monitor digoxin levels, especially during the initial phase of treatment or when adjustments are made. Healthcare providers also monitor electrolyte levels, such as potassium and magnesium, because imbalances can increase the risk of side effects.

Possible Benefits

Patients with specific heart conditions may experience significant symptom relief with digoxin. It can reduce episodes of rapid heart rate, improve exercise tolerance, and decrease symptoms like fatigue and shortness of breath. For individuals with atrial fibrillation, digoxin is useful as part of a broader treatment plan to control heart rate and maintain stable cardiovascular function. While it does not cure underlying heart issues, it can enhance overall heart function and patient well-being when used appropriately.

Potential Side Effects and Risks

Like all medications, digoxin carries potential side effects. Common adverse effects include nausea, vomiting, dizziness, and blurred vision, particularly yellow-green halos around lights. More severe toxicity can lead to irregular heart rhythms, which can be dangerous. Symptoms of toxicity include confusion, weakness, and arrhythmias, and require immediate medical attention. The risk of toxicity increases with factors such as kidney impairment, electrolyte disturbances, and drug interactions. Therefore, regular health monitoring is essential when on digoxin therapy.

Precautions and Interactions

Patients should inform healthcare providers about all other medications they are taking, as digoxin interacts with many drugs, including diuretics, certain antibiotics, and drugs used for heart rhythm management. These interactions may alter digoxin levels or exacerbate side effects. Additionally, conditions like kidney disease or thyroid problems can influence how digoxin is processed in the body. Proper dosing and consistent monitoring can help prevent adverse events. Patients are advised to report any symptoms of toxicity promptly and adhere strictly to medical advice regarding blood tests and medication adjustments.

See Also

Lanoxin
Lanoxin

From £0.48 per dose