| Package | Dosage | Price | Price per Dose | |
|---|---|---|---|---|
| Dosage: 10mg | ||||
| 360 pill | 10mg | £276.36 | £0.77 | |
| 180 pill | 10mg | £151.17 | £0.84 | |
| 120 pill | 10mg | £108.65 | £0.91 | |
| 90 pill | 10mg | £86.21 | £0.96 | |
| 60 pill | 10mg | £61.40 | £1.03 | |
| 30 pill | 10mg | £34.24 | £1.12 | |
| Dosage: 20mg | ||||
| 360 pill | 20mg | £446.44 | £1.24 | |
| 180 pill | 20mg | £242.11 | £1.35 | |
| 120 pill | 20mg | £177.15 | £1.48 | |
| 90 pill | 20mg | £144.08 | £1.59 | |
| 60 pill | 20mg | £103.92 | £1.74 | |
| 30 pill | 20mg | £56.68 | £1.89 | |
| 10 pill | 20mg | £20.07 | £2.06 | |
Piroxicam Description
Introduction to Piroxicam
Piroxicam is a non-steroidal anti-inflammatory drug (NSAID) widely used to manage pain and inflammation associated with various musculoskeletal conditions. It belongs to the oxicam class of NSAIDs and is known for its effectiveness in reducing symptoms of arthritis, including rheumatoid arthritis and osteoarthritis. As an oral medication, Piroxicam offers a convenient option for patients seeking relief from chronic inflammatory conditions.
Mechanism of Action
This medication works by inhibiting cyclooxygenase (COX) enzymes, primarily COX-1 and COX-2. These enzymes are responsible for producing prostaglandins, which are compounds that induce inflammation, pain, and fever. By blocking COX activity, Piroxicam decreases prostaglandin synthesis, leading to reduced inflammation and pain. Its long half-life allows for once-daily dosing, making it a preferred choice for many patients.
Uses and Medical Benefits
Piroxicam is primarily prescribed for long-term management of inflammatory conditions like rheumatoid arthritis and osteoarthritis. It helps alleviate pain, stiffness, and swelling, thereby improving joint and physical functioning. In some cases, it is also used for acute pain episodes and other conditions involving inflammation. Its potent anti-inflammatory effects can significantly improve quality of life, especially in patients with chronic joint diseases.
Dosage and Administration
The typical dose of Piroxicam varies depending on the condition being treated and patient response. Usually, adults take 20 mg once or twice daily. It's important to follow the physician’s instructions and not to exceed the prescribed dose. The medication is best taken with food or a full glass of water to minimize gastrointestinal discomfort. Regular monitoring and follow-up with a healthcare provider are recommended to assess effectiveness and adjust dosage if necessary.
Possible Side Effects
While Piroxicam is effective for many patients, it can cause side effects. Common adverse reactions include stomach pain, nausea, indigestion, and headache. Serious but less common side effects involve gastrointestinal bleeding, ulcers, kidney problems, and cardiovascular issues. Patients with a history of heart disease or gastrointestinal bleeding should use Piroxicam with caution and under medical supervision. Reporting any unusual symptoms early can help prevent more severe complications.
Precautions and Interactions
Piroxicam should be used cautiously in individuals with existing health conditions such as liver or kidney impairment, high blood pressure, or a history of ulcers. It may interact with other medications like blood thinners, other NSAIDs, or certain antihypertensives. Combining Piroxicam with these drugs can increase the risk of bleeding or other adverse effects. Before starting treatment, a healthcare provider should review all current medications and medical history.
Conclusion
Piroxicam is a potent NSAID that provides effective relief from pain and inflammation associated with chronic joint diseases. Its long duration of action allows for simple dosing schedules, contributing to better patient adherence. However, its use requires careful consideration of potential side effects and drug interactions. Proper medical guidance is essential to maximize benefits and minimize risks when using Piroxicam for therapeutic purposes.